βhCG-secreting osteosarcoma

Case Report: An Unusual Cause of Elevated Serum Total βhCG

Human chorionic gonadotropin (hCG), a heterodimeric hormone consisting of an alpha (a) and a beta (β) subunit, is used as a marker for the diagnosis of pregnancy, congenital defects, and choriocarcinoma. After excluding the common causes of elevated serum hCG, laboratory identification of false-positive or true results assists in guiding clinical management. Options include testing urine for hC...

Calcaneal Osteosarcoma; a Case Report

Osteosarcoma of the foot is rare and, when presents, commonly observed in adults. We report a case of osteosarcoma of the calcaneus in an 11-year-old girl who was presented with a 4-month history of pain and swelling on her left ankle and inability to walk in her left lower extremity. On examination, there was a diffuse swelling involving her left ankle joint and foot. The radiograph showed sof...

[Osteosarcoma].

Findings from molecular genetic and cytogenetic investigations suggest that mutations in suppressor genes play a key role in osteosarcoma pathogenesis. RB and p53 are frequently involved and are speculated to be indispensable components. Alterations in putative suppressor genes on chromosomes 18q and 3q additionally may be involved in various patterns. The high resolution of magnetic resonance ...

همبستگی میان βhCG و آزمونهای عملکرد تیروئیدی در آبستنی مول‌دار

: با توجه به دیدگاههای ضد و نقیض در مورد نقش هورمون کوریونیک گونادوتروپین در تحریک فعالیت تیروئید در بیماران با تومورهای تروفوبلاستیک، ‌بویژه مول هیداتیدیفورم، این مطالعه بر روی 48 بیمار با مول هیداتیدیفورم که سطح سرمی βhCG آنان به زیر mIU/l5، ظرف مدت 18 ماه پس از تخلیه رحمی رسیده بود، انجام گردید. سطح سرمی βhCG ، توتال T3، T4 و TSH زمانی که βhCG بالا بوده و زمانی که به زیر mIU/ml5 رسیده بود، د...

A FSH-Secreting Pituitary Macroadenoma Causing A Testosterone Deficiency Syndrome